In race for monkeypox vaccines, experts see repeat of COVID

Jul 29, 2022, 11:38 AM | Updated: Jul 30, 2022, 10:23 am
FILE - A sign urges the release of the monkeypox vaccine during a protest in San Francisco, July 18...

FILE - A sign urges the release of the monkeypox vaccine during a protest in San Francisco, July 18, 2022. The mayor of San Francisco announced a legal state of emergency Thursday, July 28, 2022, over the growing number of monkeypox cases. Public health officials warn that moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans. (AP Photo/Haven Daley, File)

(AP Photo/Haven Daley, File)

              Vials of single doses of the Jynneos vaccine for monkeypox are seen in the vaccine hub at Zuckerberg San Francisco General Hospital on Friday, July 29, 2022, in San Francisco. (Lea Suzuki/San Francisco Chronicle via AP)
            
              Jonathan Parducho, a pharmacist, opens a freezer transport box which was delivered earlier containing the Jynneos vaccine for monkeypox, next to a smaller refrigerated transport box containing the Jynneos vaccine to be picked up by an external distributor, in the vaccine hub at Zuckerberg San Francisco General Hospital on Friday, July 29, 2022, in San Francisco. (Lea Suzuki/San Francisco Chronicle via AP)
            
              FILE - Empty vials of vaccines against Monkeypox lie on a table after being used to vaccinate people at a medical center in Barcelona, Spain, Tuesday, July 26, 2022.  Public health officials warn that moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans. (AP Photo/Francisco Seco, File)
            
              FILE - Daniel Rofin, 41, receives a vaccine against Monkeypox from a health professional in medical center in Barcelona, Spain, Tuesday, July 26, 2022. Public health officials warn that moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans. (AP Photo/Francisco Seco, File)
            
              FILE - A sign urges the release of the monkeypox vaccine during a protest in San Francisco, July 18, 2022. The mayor of San Francisco announced a legal state of emergency Thursday, July 28, 2022, over the growing number of monkeypox cases. Public health officials warn that moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans. (AP Photo/Haven Daley, File)

LONDON (AP) — Moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans, public health officials are warning.

Critics fear a repeat of the catastrophic inequity problems seen during the coronavirus pandemic.

“The mistakes we saw during the COVID-19 pandemic are already being repeated,” said Dr. Boghuma Kabisen Titanji, an assistant professor of medicine at Emory University.

While rich countries have ordered millions of vaccines to stop monkeypox within their borders, none have announced plans to share doses with Africa, where a more lethal form of monkeypox is spreading than in the West.

To date, there have been more than 21,000 monkeypox cases reported in nearly 80 countries since May, with about 75 suspected deaths in Africa, mostly in Nigeria and Congo. On Friday, Brazil and Spain reported deaths linked to monkeypox, the first reported outside Africa. On Saturday, Spain reported a second monkeypox death.

“The African countries dealing with monkeypox outbreaks for decades have been relegated to a footnote in conversations about the global response,” Titanji said.

Scientists say that unlike campaigns to stop COVID-19, mass vaccination against monkeypox won’t be necessary. They think targeted use of the available doses, along with other measures, could shut down the expanding epidemics recently designated by the World Health Organization as a global emergency.

Yet while monkeypox is much harder to spread than COVID-19, experts warn that if the disease spills over into general populations — currently in Europe and North America it is circulating almost exclusively among gay and bisexual men — the need for vaccines could intensify, especially if the virus becomes entrenched in new regions.

On Thursday, the Africa Centers for Disease Control and Prevention called for the continent to be prioritized for vaccines, saying it was again being left behind.

“If we’re not safe, the rest of the world is not safe,” said Africa CDC’s acting director, Ahmed Ogwell.

Although it has been endemic in parts of Africa for decades, monkeypox mostly jumps into people from infected wild animals and has not typically spread very far beyond the continent.

Experts suspect the monkeypox outbreaks in North America and Europe may have originated in Africa long before the disease started spreading via sex at two raves in Spain and Belgium. Currently, more than 70% of the world’s monkeypox cases are in Europe, and 98% of cases are in men who have sex with men.

WHO is developing a vaccine-sharing mechanism for affected countries, but has released few details about how it might work. The U.N. health agency has made no guarantees about prioritizing poor countries in Africa, saying only that vaccines would be dispensed based on epidemiological need.

Some experts worry the mechanism could duplicate the problems seen with COVAX, created by WHO and partners in 2020 to try to ensure poorer countries would get COVID-19 shots. That missed repeated targets to share vaccines with poorer nations and at times relied on donations.

“Just asking countries to share is not going to be enough,” said Sharmila Shetty, a vaccines adviser for Medecins Sans Frontieres. “The longer monkeypox circulates, the greater chances it could get into new animal reservoirs or spread to” the human general population, she said. “If that happens, vaccine needs could change substantially.”

At the moment, there is only one producer of the most advanced monkeypox vaccine: the Danish company Bavarian Nordic. Its production capacity this year is about 30 million doses, with about 16 million vaccines available now.

In May, Bavarian Nordic asked the U.S. to release more than 215,000 doses it was due to receive, “to assist with international requests the company was receiving,” and the U.S. complied, according to Bill Hall, a spokesman for the department of Health and Human Services. The U.S. will still receive the doses, but at a later date.

The company declined to specify which countries it was allocating doses for.

Hall said the U.S. has not made any other promises to share vaccines. The U.S. has ordered by far the most number of doses, with 13 million reserved, although only about 1.4 million have been delivered.

Some African officials said it would be wise to stockpile some doses on the continent, especially given the difficulties Western countries were having stopping monkeypox.

“I really didn’t think this would spread very far because monkeypox does not spread like COVID,” said Salim Abdool Karim, an infectious diseases epidemiologist at the University of KwaZulu-Natal in South Africa. “Africa should procure some vaccines in case we need them, but we should prioritize diagnostics and surveillance so we know who to target,” he said. “Normally, you’re able to get ahead of a disease like monkeypox, but I am concerned (the number of new cases) hasn’t started coming down yet.”

Dr. Ingrid Katz, a global health expert at Harvard University, said the monkeypox epidemics were “potentially manageable” if the limited vaccines were distributed appropriately. She believed it was still possible to prevent monkeypox from turning into a pandemic, but that “we need to be thoughtful in our prevention strategies and rapid in our response.”

In Spain, which has Europe’s biggest monkeypox outbreak, demand for vaccines far exceeds supply.

“There is a real gap between the number of vaccines that we currently have available and the people who could benefit,” said Pep Coll, a medical director at a Barcelona health center that was dispensing shots this week.

Daniel Rofin, 41, was more than happy to be offered a dose recently. He said he decided to get vaccinated for the same reasons he was immunized against COVID-19.

“I feel reassured it is a way to stop the spread,” he said. “We (gay men) are a group at risk.”

___

Joseph Wilson and Renata Brito in Barcelona, Spain, Chris Megerian in Washington and Cara Anna in Nairobi, Kenya contributed to this report.

Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

AP

fishery...
Associated Press

Much of drought-plagued West Coast faces salmon fishing ban

The surreal and desperate scramble boosted the survival rate of the hatchery-raised fish, but still it was not enough to reverse the declining stocks in the face of added challenges.
2 days ago
UCLA's Jaime Jaquez Jr. (24) shoots while defended by Gonzaga's Rasir Bolton (45) in the first half...
Associated Press

Gonzaga beats UCLA 79-76 in Sweet 16 on Strawther’s shot

Julian Strawther hit a 3-pointer with 6 seconds left to answer a 3-pointer by UCLA's Amari Bailey, lifting Gonzaga to a wild 79-76 NCAA Tournament win over UCLA Thursday night in the Sweet 16.
2 days ago
transportation...
Associated Press

Officials: Safety device, human error derailed Wash. train

A safety device failed, knocking a train off the tracks last week, spilling diesel after leaving an oil refinery in Anacortes.
2 days ago
File - Credit cards as seen July 1, 2021, in Orlando, Fla. A low credit score can hurt your ability...
Associated Press

What the Fed rate increase means for your credit card bill

The Federal Reserve raised its key rate by another quarter point Wednesday, bringing it to the highest level in 15 years as part of an ongoing effort to ease inflation by making borrowing more expensive.
3 days ago
police lights distracted drivers shooting...
Associated Press

Authorities: Missing mom, daughter in Washington found dead

A missing Washington state woman and her daughter were found dead Wednesday, according to police.
3 days ago
Google...
Associated Press

Google’s artificially intelligent ‘Bard’ set for next stage

Google announced Tuesday it's allowing more people to interact with “ Bard,” the artificially intelligent chatbot the company is building to counter Microsoft's early lead in a pivotal battleground of technology.
4 days ago

Sponsored Articles

Emergency Preparedness...

Prepare for the next disaster at the Emergency Preparedness Conference

Being prepared before the next emergency arrives is key to preserving businesses and organizations of many kinds.
SHIBA volunteer...

Volunteer to help people understand their Medicare options!

If you’re retired or getting ready to retire and looking for new ways to stay active, becoming a SHIBA volunteer could be for you!
safety from crime...

As crime increases, our safety measures must too

It's easy to be accused of fearmongering regarding crime, but Seattle residents might have good reason to be concerned for their safety.
Comcast Ready for Business Fund...
Ilona Lohrey | President and CEO, GSBA

GSBA is closing the disparity gap with Ready for Business Fund

GSBA, Comcast, and other partners are working to address disparities in access to financial resources with the Ready for Business fund.
SHIBA WA...

Medicare open enrollment is here and SHIBA can help!

The SHIBA program – part of the Office of the Insurance Commissioner – is ready to help with your Medicare open enrollment decisions.
Lake Washington Windows...

Choosing Best Windows for Your Home

Lake Washington Windows and Doors is a local window dealer offering the exclusive Leak Armor installation.
In race for monkeypox vaccines, experts see repeat of COVID